Published: November 24, 2017
As with other water soluble vitamins, small amounts of vitamin B6 can be stored in your body, primarily in muscles. However, foods containing vitamin B6 should be included as part of your daily food intake.
There are three forms of this vitamin: Pyridoxine, Pyridoxal, and Pyridoxamine. These three forms of vitamin B6 can be converted into the coenzyme pyridoxal phosphate (PLP).
Vitamin B6 as coenzyme PLP, interacts with more than 100 enzymes in a variety of metabolic reactions such as:
- Amino acid metabolism: PLP transfers amino groups (NH2) from an amino acid to a keto acid which enables the synthesis of non-essential amino acids
- Protein metabolism
- Urea metabolism
- Conversion of tryptophan to niacin (vitamin B3) or to serotonin (neurotransmitter)
- Conversion of tyrosine to dopamine (neurotransmitter)
- Synthesis of heme (non -protein part of hemoglobin), blood protein and red blood cell synthesis
- Synthesis of nucleic acids (DNA and RNA)
- Synthesis of lecithin (a phospholipid)
- Initial step of glycogen metabolism and degradation into glucose
- Synthesis of cysteine from methionine
- Formation of glycine from serine
- Sphingolipid synthesis: Sphingomyelins are found in large amounts in the myelin sheath of nerve tissues
- Synthesis of carnitine required for fatty acid oxidation
- Synthesis of taurine a neuromodulatory compound generated from cysteine metabolism
- Steroid hormone production
- May influence cognitive performance and immune function
Recommended daily allowance (RDA)
Gropper, S.S., Smith, J.L. & Groff, J.L. (2005). Advanced Nutrition and Human Metabolism (4thEd.). Belmont, CA: Thomson Wadsworth.
. Whitney, E. & Rady Rolfes, S. (2005). Understanding Nutrition. Belmont, CA: Thomson Wadsworth
Centre for Science in the Public Interest (August, 2011). Nutrition Action Health Letter (June 2008, January 2011))