Ultra trace minerals: Part 2
Published: August 16, 2019
Quick facts:
Ultra trace elements or minerals include aluminum (aluminium), arsenic, boron, bromine, cadmium, chromium copper, fluoride, germanium, iodine, lead, lithium, molybdenum, nickel, rubidium, selenium, silicon, tin and vanadium.
This article considers vanadium, aluminium, bromine, cadmium, germanium, lead, lithium, rubidium and tin
- Little research into essentiality of vanadium, aluminum, bromine, cadmium, germanium, lead, lithium, rubidium and tin
- lead is known to be toxic to humans.
Despite the lack of understanding about these minerals and requirement for human health some are included in multivitamin supplements.
Vanadium
- Vanadium exists in several forms which in solution give a range of colours from blue to yellow/orange.
- Dietary sources: Cereals and grain products, fats/oils, shell fish, black pepper, parsley, dill seed, canned apple juice, mushrooms, sweeteners, and beer and wine
- Currently no recommended daily intake
- The tolerable upper level for vanadium has been established at 1.8 mg/day.
- Toxicity: Has occurred above 10 mg doses. Symptoms include green tongue, gastrointestinal cramps, diarrhea, disturbed mental function, high blood pressure and renal complications.
- Deficiency: associated with thyroid gland function, iodine metabolism, restricted growth rate, peri-natal survival, physical appearance, and changes in volume of red blood cells in your blood.
Aluninium
- Aluminum or aluminium does not appear to have any human biological function.
- High doses may lead to negative health effects such as: changes in your blood-brain barrier function, allergenic reactions through ingestion such as dermatitis, digestive disorders, and toxicity if more than 40mg/day per kg of body weight is ingested
- Aluminium absorption from aluminium cookware is significantly increased when acidic foods or liquids cooked in aluminium cookware
- Aluminium can accumulate in nervous tissue.
- May be an association between aluminium and estrogen related gene expression in laboratory cultured human breast cancer cells
Bromine
- A biological role for bromine has not yet been specified
- Bromine as bromide potentially an essential element for humans: may be necessary for the proper function of a specific protein required in your extracellular framework.
Cadmium
- A biological role for cadmium in humans has not yet been identified.
- Cadmium is found in humans concentrated in your kidneys.
- At high levels of absorption cadmium can be toxic: Inhalation of cadmium fumes may lead to lung disease and death.
- Sources of cadmium: fertilizers, soils, many manufacturing processes, bread, root crops and vegetables, crustaceans, mollusks, offal, and algae products and cigarettes
- Cadmium as a carcinogen: may induce breast cancer, occupational exposure may lead to lung and prostate cancer, dietary exposure may increase risk of osteoporosis, and endometrial, breast and prostate cancer.
- Cadmium and disease: increased risk cardiovascular disease, hypertension, atherosclerosis, and kidney disease.
- Toxicity: may be reduced by the presence of zinc, copper, calcium, iron, selenium and vitamin C
Germanium
- Germanium is not essential to human health: is ingested in only very small amounts
- Organic and inorganic germanium supplements may have the potential to treat leukemia and lung cancer.
- Inorganic supplements may be harmful and over time and may result in kidney dysfunction, fatty liver, and peripheral nerve damage.
Lead
- Lead is highly toxic to human health
- Deficiency in rats and pigs may lead to anaemia, restricted growth, and altered iron metabolism
- Ingestion is the principle source of lead exposure, can also be inhaled and absorbed through contact.
- Maximum level of lead allowed in pharmaceuticals is 1.0 mcg/g which is representative of maximum daily intake for humans.
- Adverse effects of lead on human metabolism: inhibits iron absorption, competes with calcium for absorption and metabolic activities, may adversely affect cognition, nerves, kidneys, immune system cardiovascular system, and fertility
- Dietary sources of lead: water, fruits, vegetables, and alcohol may be contaminated with lead from various sources
Lithium
- Lithium is found in most animal tissue in trace amount as well as in plants, plankton and invertebrates.
- Lithium salts are used in the treatment of bipolar disorder, schizoaffective disorder and cyclic major depression.
- If used by women in the first trimester of pregnancy increased risk of Ebstein’s cardiac anomaly in offspring.
Rubidium
- No biological role identified, essentiality not determined, but rubidium is used to detect brain tumours
- Rubidium tends to concentrate inside your body cells.
- Toxicity: not thought to be toxic
- Negative health effects are not seen with up to 36 g of rubidium. In rats death resulted when greater than 50% of potassium was substituted by rubidium in muscle.
- May influence depression in persons undergoing dialysis
Tin
- There are no known biological roles for tin which can be absorbed into your body through inhalation, skin contact and eye contact.
- Organotin compounds appear to be highly toxic.
- Over exposure may inhibit copper and zinc metabolism.
- Tin is found in dental products
Link to the full article to learn more about these Ultra trace minerals
References
1.
Gropper, S.S., Smith, J.L. & Groff, J.L. (2005). Advanced Nutrition and Human Metabolism (4thEd.). Belmont, CA: Thomson Wadsworth
2.
Centre for Science in the Public interest (CSPI) November 2013